Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798862 | 0.80 | TTR (0.42) | HTR6RCE1TTRCA12CA1 | |
| SCHEMBL11230129 | 0.80 | RCE1 (0.38) | HTR6RCE1TTRCA12CA1 | |
| SCHEMBL3137448 | 0.78 | ELANE (0.43) | HTR6RCE1TTR | |
| SCHEMBL11229501 | 0.76 | RCE1 (0.64) | HTR6RCE1 | |
| SCHEMBL6109454 | 0.72 | DAGLA (0.41) | — | |
| SCHEMBL5051762 | 0.72 | TOP2A (0.59) | RCE1 | |
| SCHEMBL19499377 | 0.70 | RCE1 (0.53) | HTR6RCE1 | |
| SCHEMBL28856792 | 0.70 | MAOB (0.41) | CA12CA9 | |
| SCHEMBL9563347 | 0.69 | PSMB8 (0.35) | — | |
| SCHEMBL4750075 | 0.69 | PKLR (0.38) | RCE1TTRCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225127-B1 | DETECTION, DETERMINATION, AND QUANTITATION OF CERTAIN ANIONS INVOLVING THE QUENCHING OF A FLUORESCENT LABEL ATTACHED TO A METALLOENZYME DUE TO FLUORESCENCE ENERGY TRANSFER TO A COLORED INHIBITOR | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-05-01 | — | — | US | disclosed |
| US-6197258-B1 | DETECTOR FOR DETERMINING AQUEOUS METAL ION CONCENTRATION INCLUDING A PHOTOLUMINESCENT LABEL BOUND TO AN ANALYTE BINDING MACROMOLECULE OF HUMAN APOCARBONIC ANHYDRASE OR DERIVATIVE | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-03-06 | — | — | US | disclosed |
| US-5952236-A | Enzyme-based fluorescence biosensor for chemical analysis | PATCHAN, MARCIA W. | 1999-09-14 | — | — | US | disclosed |