Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 12/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 12/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19499377 | 0.84 | RCE1 (0.53) | RCE1TOP2APTPN1PTPN5HSPD1 | |
| SCHEMBL5051762 | 0.80 | TOP2A (0.59) | RCE1TOP2APTPN1PTPN5HSPD1 | |
| SCHEMBL121325 | 0.80 | TOP2A (0.65) | RCE1TOP2ARAB9ASMN1; SMN2HIF1A | |
| SCHEMBL28558754 | 0.77 | CYP2C9 (0.51) | RCE1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL27798862 | 0.76 | TTR (0.42) | RCE1HTR3AHSD17B10ALDH1A1HTR6 | |
| SCHEMBL7907329 | 0.76 | HTR6 (0.39) | RCE1HTR6 | |
| SCHEMBL11230129 | 0.76 | RCE1 (0.38) | RCE1HTR6 | |
| SCHEMBL56593 | 0.76 | TOP2A (0.53) | RCE1TOP2APTPN1PTPN5HSPD1 | |
| SCHEMBL28868160 | 0.76 | TOP2A (0.47) | RCE1TOP2APTPN1PTPN5PTPN2 | |
| SCHEMBL28926584 | 0.74 | TOP2A (0.59) | RCE1TOP2ARAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012178-B1 | BENZOXAZOL DERIVATIVES, METHODS FOR THEIR PREPARATION, COSMETIC COMPOSITIONS CONTAINING SUCH COMPOUNDS, USE OF SUCH COMPOUNDS AS UV-A FILTERS AND METHOD OF PROTECTING THE SKIN AND HAIR AND METHOD OF STABILIZING COSMETIC COMPOSITIONS | Richardson-Vicks, Inc. (US) | 1982-12-08 | — | — | EP | disclosed |