SCHEMBL7907379

SCHEMBL7907379

CCCCCCc1cnc(-c2ccc(OCCCCC)cc2)nc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.63
RAB9A P51151 5/20 0.63
KDM4E B2RXH2 4/20 0.63
NPC1 O15118 3/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
HSD17B10 Q99714 2/20 0.63
ALDH1A1 P00352 4/20 0.60
MAPT P10636 3/20 0.60
HPGD P15428 3/20 0.60
MEN1 O00255 2/20 0.60
USP2 O75604 2/20 0.60
KMT2A Q03164 2/20 0.60
GAA P10253 1/20 0.60
L3MBTL1 Q9Y468 2/20 0.56
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
CYP3A4 P08684 2/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9436035 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL9636338 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL13029249 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10342131 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL9241350 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL7910730 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL8961773 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL7121080 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL4815333 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL2774683 1.00 RARB (0.63) RARBRAB9AKDM4ENPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US claimed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
EP-0394417-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-08-04 EP disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5536442-A ELECTROOPTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-16 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0394417-B1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1994-10-26 EP disclosed
US-5324449-A Substituted phenyl trifluoromethyl ethers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-28 US disclosed
EP-0366985-B1 Super twist liquid crystal display MERCK PATENT GMBH (DE) 1994-04-06 EP disclosed
US-5248447-A 2,3-difluorohydroquinone derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-09-28 US disclosed
EP-0207975-A1 LIQUID CRYSTALLINE PHASES. MERCK PATENT GMBH (DE) 1987-01-14 EP disclosed
EP-0199004-A1 Pyrimidine derivatives MERCK PATENT GmbH (DE) 1986-10-29 EP disclosed
WO-1986005799-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-10-09 WO disclosed
WO-1986004081-A1 LIQUID CRYSTALLINE PHASES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-07-17 WO disclosed
WO-1986004060-A1 PYRIMIDINES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-07-17 WO disclosed
WO-1986002375-A1 LIQUID CRYSTAL COMPOSITION MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-04-24 WO disclosed
EP-0174541-A1 Electrooptic display element MERCK PATENT GmbH (DE) 1986-03-19 EP disclosed
EP-0152808-A2 Nitrogen containing heterocycles MERCK PATENT GmbH (DE) 1985-08-28 EP disclosed
EP-0151446-A2 Liquid crystal phase MERCK PATENT GmbH (DE) 1985-08-14 EP disclosed
EP-0149208-A2 Ethane derivatives MERCK PATENT GmbH (DE) 1985-07-24 EP disclosed