Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436035 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9636338 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7907379 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL13029249 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL10342131 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9241350 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7910730 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7121080 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL4815333 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2774683 | 1.00 | RARB (0.63) | RARBRAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8821992-B2 | Oligosiloxane modified liquid crystal formulations and devices using same | DOW CORNING CORPORATION (US) | 2014-09-02 | — | — | US | disclosed |
| US-8368831-B2 | Oligosiloxane modified liquid crystal formulations and devices using same | DOW CORNING CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100283925-A1 | OLIGOSILOXANE MODIFIED LIQUID CRYSTAL FORMULATIONS AND DEVICES USING SAME | DOW CORNING CORPORATION (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100283927-A1 | OLIGOSILOXANE MODIFIED LIQUID CRYSTAL FORMULATIONS AND DEVICES USING SAME | DOW CORNING CORPORATION (US) | 2010-11-11 | — | — | US | disclosed |
| US-5518653-A | LIQUID CRYSTAL | HOFFMANN-LA ROCHE INC. (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0523543-B1 | Chiral piperazine derivatives | HOFFMANN LA ROCHE (CH) | 1996-02-07 | — | — | EP | disclosed |
| EP-0457105-B1 | Chiral dioxanes as components of liquid crystal mixtures | HOFFMANN LA ROCHE (CH) | 1995-07-26 | — | — | EP | disclosed |
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5356559-A | Optically active piperazinyl derivatives as liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0247466-B1 | Liquid-crystal derivatives of phenyl benzoate | HOFFMANN LA ROCHE (CH) | 1993-11-24 | — | — | EP | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |
| US-5082589-A | Liquid crystalline esters | HOFFMANN-LA ROCHE INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0457105-A1 | Chiral dioxanes as components of liquid crystal mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| US-4925278-A | Liquid crystalline esters | HOFFMANN-LA ROCHE INC. (US) | 1990-05-15 | — | — | US | disclosed |
| US-4906401-A | Use of liquid-crystal 5-phenylpyrimidine derivatives as components of smectic liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |
| EP-0343487-A1 | Cyclohexyl esters of alpha-fluoro/carboxylic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| US-4830470-A | Liquid crystalline esters | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0284008-A2 | Use of derivatives of 5-phenyl pyrimidine as components of smectic liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-28 | — | — | EP | disclosed |
| EP-0247466-A2 | Liquid-crystal derivatives of phenyl benzoate | F. HOFFMANN-LA ROCHE AG (CH) | 1987-12-02 | — | — | EP | disclosed |