Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | GLA | P06280 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914303 | 0.90 | MAOB (0.60) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL24205477 | 0.90 | MAOB (0.60) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL7914328 | 0.89 | MAOB (0.61) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL7907372 | 0.87 | AR (0.54) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL7914330 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL5831209 | 0.85 | KMT2A (0.59) | KDM4EKMT2AGLAGAAPOLB | |
| SCHEMBL7914299 | 0.85 | KMT2A (0.59) | KDM4EKMT2AGLAGAAPOLB | |
| SCHEMBL7914273 | 0.84 | KMT2A (0.60) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL8834993 | 0.84 | KDM4E (0.59) | ALDH1A1KDM4EKMT2AGLAGAA | |
| SCHEMBL29408446 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |