Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | AGER | Q15109 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920960 | 0.91 | AGER (0.60) | ARPPARAAGERKDM4EALDH1A1 | |
| SCHEMBL7907388 | 0.87 | ALDH1A1 (0.60) | ARHTTPOLBAPEX1TDP1 | |
| SCHEMBL8835405 | 0.85 | AR (0.54) | ARPPARAAGERHTTKDM4E | |
| SCHEMBL7914253 | 0.85 | AGER (0.62) | ARPPARAAGERMAOB | |
| SCHEMBL5831209 | 0.82 | KMT2A (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL7914299 | 0.82 | KMT2A (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL7914273 | 0.81 | KMT2A (0.60) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL7914329 | 0.81 | AGER (0.60) | ARAGERKDM4EALDH1A1KMT2A | |
| SCHEMBL7914259 | 0.80 | AR (0.54) | ARPPARAAGERKDM4EALDH1A1 | |
| SCHEMBL7917907 | 0.80 | KMT2A (0.60) | HTTPOLBAPEX1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |