Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906278 | 0.88 | LTA4H (0.51) | MAOBRAB9AHTTL3MBTL1KDM4E | |
| SCHEMBL16263296 | 0.87 | MAOB (0.61) | MAOBRAB9AHTTL3MBTL1KDM4E | |
| SCHEMBL10876065 | 0.85 | ALDH1A1 (0.53) | MAOBRAB9AHTTL3MBTL1KDM4E | |
| SCHEMBL3840708 | 0.83 | MAOB (0.55) | MAOBALDH1A1LTA4HMAPTSMN1; SMN2 | |
| SCHEMBL30633275 | 0.83 | MAOB (0.55) | MAOBALDH1A1LTA4HMAPTSMN1; SMN2 | |
| SCHEMBL3839157 | 0.83 | ALDH1A1 (0.54) | MAOBALDH1A1LTA4HMAPTSMN1; SMN2 | |
| SCHEMBL3838974 | 0.83 | ALDH1A1 (0.54) | MAOBALDH1A1LTA4HMAPTSMN1; SMN2 | |
| SCHEMBL3838956 | 0.81 | SMN1; SMN2 (0.58) | MAOBALDH1A1LTA4HTDP1LMNA | |
| SCHEMBL13883739 | 0.81 | MAOB (0.64) | MAOBRAB9AHTTL3MBTL1KDM4E | |
| SCHEMBL10801659 | 0.80 | MAOB (0.67) | MAOBRAB9AHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064041-A9 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE INC (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1100519-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | Advanced Medicine, Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999064041-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |