Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962253 | 0.95 | MAOB (0.61) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11557673 | 0.93 | KDM4E (0.60) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3191667 | 0.92 | MAOB (0.58) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7910785 | 0.91 | MAOB (0.59) | MAOBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL29032389 | 0.91 | SMPD1 (0.53) | FFAR4RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL7910894 | 0.90 | FFAR4 (0.65) | MAOBFFAR4PPARAMRGPRX4 | |
| SCHEMBL7910948 | 0.90 | MAOB (0.57) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7911112 | 0.90 | MAOB (0.57) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21924287 | 0.89 | MAOB (0.58) | MAOBFFAR4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7900610 | 0.89 | RAB9A (0.58) | MAOBRAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |