Pyridine

Pyridine

SCHEMBL7907616

O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.c1ccncc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
ALDH1A1 P00352 7/20 0.51
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
BCL9 O00512 1/20 0.47
CTNNB1 P35222 1/20 0.47
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
PTPN7 P35236 1/20 0.46
PTPN12 Q05209 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28222061 0.91 GAA (0.57) MAPTALDH1A1SMN1; SMN2GAABCL9
SCHEMBL9276769 0.87 GAA (0.57) MAPTALDH1A1SMN1; SMN2GAABCL9
Bicarbonate SCHEMBL600121 0.87 GAA (0.57) MAPTALDH1A1SMN1; SMN2GAABCL9
SCHEMBL15168 0.87 GAA (0.61) MAPTALDH1A1SMN1; SMN2GAABCL9
Ammonia Solution, Strong SCHEMBL19516242 0.85 GAA (0.59) MAPTALDH1A1SMN1; SMN2GAABCL9
SCHEMBL25236596 0.82 GAA (0.56) MAPTALDH1A1SMN1; SMN2GAABCL9
P-Nitrophenol SCHEMBL1960699 0.81 GAA (0.54) MAPTALDH1A1SMN1; SMN2GAABCL9
Ethylene Glycol SCHEMBL23277093 0.81 BCL9 (0.55) MAPTALDH1A1SMN1; SMN2GAABCL9
Pyridine SCHEMBL5452272 0.80 CYP19A1 (0.51) MAPTALDH1A1SMN1; SMN2L3MBTL1HPGD
4-Nitrobenzoyl Chloride SCHEMBL3708337 0.80 ALDH1A1 (0.73) MAPTALDH1A1L3MBTL1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082105-A1 CONTROLLED DRUG DELIVERY SYSTEM USING THE CONJUGATION OF DRUG TO BIODEGRADABLE POLYESTER MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) 2001-03-14 EP disclosed
WO-1999059548-A1 CONTROLLED DRUG DELIVERY SYSTEM USING THE CONJUGATION OF DRUG TO BIODEGRADABLE POLYESTER MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) 1999-11-25 WO disclosed