Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 13/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.45 |
| ▸ | S100A9 | P06702 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789716 | 0.82 | CYP17A1 (0.42) | SLC22A12S100A9MEN1POLBKMT2A | |
| SCHEMBL114826 | 0.82 | PIK3CD (0.52) | — | |
| SCHEMBL29556703 | 0.82 | PIK3CD (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL28553362 | 0.81 | PIK3CD (0.51) | — | |
| SCHEMBL17969358 | 0.79 | HPGD (0.44) | PTGS1PTGS2S100A9MEN1POLB | |
| SCHEMBL3117652 | 0.78 | PIK3CG (0.44) | S100A9MEN1POLBKMT2A | |
| SCHEMBL16913931 | 0.78 | PIK3C3 (0.52) | S100A9MEN1POLBKMT2A | |
| SCHEMBL17022151 | 0.78 | PIK3CA (0.58) | SLC22A12S100A9MEN1POLBKMT2A | |
| SCHEMBL16461243 | 0.78 | SLC22A12 (0.48) | PTGS1PTGS2SLC22A12CA2 | |
| SCHEMBL17833788 | 0.77 | PIK3CA (0.53) | S100A9MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |