Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | MTOR | P42345 | 3/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | S100A9 | P06702 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15556197 | 0.86 | MTOR (0.55) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL28549695 | 0.85 | PIK3CG (0.50) | PIK3CAMTORS100A9MEN1KMT2A | |
| SCHEMBL16551868 | 0.85 | PIK3CA (0.55) | PIK3CAMTORMEN1KMT2APIK3CG | |
| SCHEMBL17022160 | 0.84 | LMNA (0.50) | PIK3CAMTORS100A9KMT2APIK3CG | |
| Ammonia Solution, Strong SCHEMBL28564473 | 0.84 | PIK3CG (0.49) | PIK3CAMTORS100A9MEN1KMT2A | |
| SCHEMBL22447546 | 0.84 | CCR4 (0.59) | PIK3CAMTORS100A9PIK3CGLMNA | |
| SCHEMBL15648432 | 0.84 | PIK3CG (0.49) | PIK3CAMTORS100A9PIK3CGPIK3R1 | |
| SCHEMBL358926 | 0.84 | PIK3CG (0.63) | PIK3CAMTORS100A9PIK3CGSLC40A1 | |
| SCHEMBL21513750 | 0.83 | CACNA1B (0.56) | PIK3CAMTORKDM1ASLC40A1LMNA | |
| SCHEMBL29969883 | 0.83 | CACNA1B (0.56) | PIK3CAMTORKDM1ASLC40A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120737-A1 | SUBSTITUTED PYRIDOPYRIMIDINE COMPOUNDS, PREPARATION METHODS THEREFOR AND USES THEREOF | 北大方正集团有限公司 | 2015-08-20 | — | — | WO | disclosed |