Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | MDH2 | P40926 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911129 | 0.86 | MAOB (0.75) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL16239894 | 0.85 | FFAR1 (0.51) | MAOBMAOAMEN1SLC26A4KMT2A | |
| SCHEMBL7909052 | 0.84 | MRGPRX4 (0.53) | MAOBMEN1SLC26A4KMT2AMRGPRX4 | |
| SCHEMBL4212043 | 0.83 | MAOB (0.58) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL15615390 | 0.83 | MAOB (0.58) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL365812 | 0.82 | NPC1 (0.64) | MAOBMAOAMEN1KMT2AMRGPRX4 | |
| SCHEMBL7908741 | 0.82 | MAOB (0.56) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7911261 | 0.82 | MAOB (0.56) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL7900785 | 0.81 | MAOB (0.75) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL629952 | 0.81 | MAOB (0.74) | MAOBMAOACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |