SCHEMBL629952

SCHEMBL629952

COC(=O)c1ccc(OCc2ccccc2)cc1O

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.74
LMNA P02545 1/20 0.61
HPGD P15428 1/20 0.61
APP P05067 1/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
PDK2 Q15119 1/20 0.57
PDK4 Q16654 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
MAOA P21397 6/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MCL1 Q07820 1/20 0.53
TSHR P16473 1/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 2,4-Dihydroxybenzoate SCHEMBL5199862 0.96 MAOB (0.68) MAOBLMNAHPGDAPPCA12
SCHEMBL29717105 0.90 MAOB (0.63) MAOBLMNAHPGDAPPCA12
SCHEMBL710202 0.90 MAOB (0.63) MAOBLMNAHPGDAPPCA12
SCHEMBL7928394 0.88 MAOB (0.59) MAOBLMNAHPGDAPPCA12
SCHEMBL4212043 0.88 MAOB (0.58) MAOBHPGDAPPCA12CA1
SCHEMBL15615390 0.88 MAOB (0.58) MAOBLMNACA12CA1CA2
SCHEMBL3962253 0.88 MAOB (0.61) MAOBLMNAHPGDNPC1RAB9A
SCHEMBL5336493 0.88 MAOB (0.61) MAOBLMNAHPGDAPPMAOA
SCHEMBL29032428 0.88 MAOB (0.58) MAOBLMNAHPGDAPPCA12
SCHEMBL7901014 0.87 MAOB (0.57) MAOBLMNAHPGDCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101795703-B Peptide tyrosinase inhibitors and uses thereof UNIV LELAND STANFORD JUNIOR 2015-05-06 CN claimed
CN-103864892-A Peptide tyrosinase inhibitors and uses thereof UNIV LELAND STANFORD JUNIOR 2014-06-18 CN claimed
US-8338364-B2 Peptide tyrosinase inhibitors and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-12-25 US claimed
US-20100330007-A1 Imrpoved Skin Brightening Compositions AMCOL INTERNATIONAL CORPORATION (US) 2010-12-30 US claimed
EP-2247279-A1 IMPROVED SKIN BRIGHTENING COMPOSITIONS AMCOL INTERNATIONAL CORPORATION (US) 2010-11-10 EP claimed
WO-2009099911-A1 IMPROVED SKIN BRIGHTENING COMPOSITIONS AMCOL INTERNATIONAL CORPORATION (US) 2009-08-13 WO claimed
EP-4168399-B1 COMPOUNDS AND THEIR USES AS MIF INHIBITORS NANJING IMMUNOPHAGE BIOMEDICAL CO LTD (CN) 2026-04-01 EP disclosed
US-20260053796-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR ARVINAS OPERATIONS INC (US) 2026-02-26 US disclosed
US-12427144-B2 Compounds and methods for the targeted degradation of androgen receptor ARVINAS OPERATIONS, INC. (US) 2025-09-30 US disclosed
CN-119039380-A Oligopeptide with whitening activity, composition and application thereof 欧诗漫生物股份有限公司 2024-11-29 CN disclosed
CN-119019490-A Active oligopeptide, tandem protein, composition and application thereof 欧诗漫生物股份有限公司 2024-11-26 CN disclosed
CN-119019489-A Melanin inhibiting active oligopeptide, tandem protein, composition and application thereof 欧诗漫生物股份有限公司 2024-11-26 CN disclosed
CN-119019309-A GPR40 agonism-SSTR 5 antagonistic double-effect compound, preparation method and application thereof 南昌大学 2024-11-26 CN disclosed
CN-1136556-A Aromatic group substituted W-amino alkyl amide and alkyl amide CIBA GEIGY CO LTD (CH) 1996-11-27 CN disclosed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP disclosed
WO-1996022775-A1 TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1996-08-01 WO disclosed
EP-0714299-A4 1996-07-10 EP disclosed
EP-0714299-A1 BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1996-06-05 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed
WO-1995002405-A1 BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053796-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR AR, NR5A1, KLK3 MAOB 2609/4885LMNA 1536/4885HPGD 3321/4885
US-12427144-B2 Compounds and methods for the targeted degradation of androgen receptor AR, KLK3, ACP3 MAOB 1259/4885LMNA 3155/4885HPGD 542/4885
US-20100330007-A1 Imrpoved Skin Brightening Compositions RARG, RBP4, RARA MAOB 3477/4885LMNA 2524/4885HPGD 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.