Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911651 | 0.89 | PDE4A (0.72) | PDE4A | |
| SCHEMBL7906783 | 0.81 | PDE4A (0.78) | PDE4A | |
| SCHEMBL7899107 | 0.77 | PDE4A (0.61) | PDE4A | |
| SCHEMBL7899116 | 0.77 | PDE4A (0.70) | PDE4A | |
| SCHEMBL7907832 | 0.76 | PDE4A (0.78) | PDE4A | |
| SCHEMBL7908344 | 0.76 | PDE4A (0.57) | PDE4A | |
| SCHEMBL7906807 | 0.76 | PDE4A (0.65) | PDE4A | |
| SCHEMBL7907997 | 0.75 | PDE4A (0.74) | PDE4A | |
| SCHEMBL7908346 | 0.75 | PDE4A (0.67) | PDE4A | |
| SCHEMBL7905253 | 0.74 | PDE4A (0.78) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | disclosed |