Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PPARG | P37231 | 17/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907641 | 0.82 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL25320973 | 0.81 | MAPT (0.55) | PPARAPPARG | |
| SCHEMBL4897797 | 0.80 | PPARG (0.58) | PPARAPPARGPPARD | |
| SCHEMBL3538865 | 0.78 | TARBP2 (0.53) | — | |
| SCHEMBL3070585 | 0.78 | PPARG (0.50) | PPARAPPARGPPARD | |
| SCHEMBL2081304 | 0.76 | FFAR1 (0.57) | PPARAPPARGPPARD | |
| SCHEMBL4851416 | 0.75 | KDM4E (0.48) | PPARAPPARGPPARD | |
| SCHEMBL7898917 | 0.75 | ATP4A (0.42) | PPARAPPARGPPARD | |
| SCHEMBL4414326 | 0.75 | POLB (0.50) | PPARAPPARGPPARD | |
| SCHEMBL5915216 | 0.75 | PPARG (0.68) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |