Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814742 | 0.93 | KDM4E (0.54) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6815855 | 0.90 | KMT2A (0.59) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6816082 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6814581 | 0.85 | POLB (0.50) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6816227 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL7908164 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6814881 | 0.82 | LMNA (0.54) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6815243 | 0.82 | KMT2A (0.70) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6816061 | 0.81 | KMT2A (0.52) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6812070 | 0.80 | KDM4E (0.69) | ALDH1A1KDM4EKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |