Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921366 | 0.91 | LTB4R2 (0.38) | LTB4R2FNTAFNTBLPAR1 | |
| SCHEMBL7917929 | 0.80 | FNTA (0.56) | FNTAFNTB | |
| Lithium Ion SCHEMBL7915168 | 0.80 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL7869070 | 0.73 | BCHE (0.50) | LTB4R2FNTAFNTBLPAR1 | |
| SCHEMBL7870287 | 0.70 | AGTR1 (0.44) | LTB4R2FNTAFNTBAGTR1AGTR2 | |
| SCHEMBL7572010 | 0.69 | MYC (0.41) | LTB4R2FNTAFNTBKDM4EPOLB | |
| SCHEMBL630063 | 0.69 | MYC (0.49) | LTB4R2FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL7869054 | 0.69 | FNTA (0.45) | LTB4R2FNTAFNTBALDH1A1 | |
| SCHEMBL7908229 | 0.69 | PTPN11 (0.35) | LTB4R2FNTAFNTB | |
| SCHEMBL7904826 | 0.68 | FNTA (0.42) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |