Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921364 | 0.92 | SLC6A4 (0.35) | FNTAFNTBLTB4R2FAAH | |
| SCHEMBL7869068 | 0.73 | ADRB1 (0.38) | LTB4R2PPARGPPARAMCL1BRS3 | |
| SCHEMBL7869050 | 0.70 | CYP1A2 (0.41) | — | |
| SCHEMBL7906933 | 0.70 | LTB4R2 (0.42) | LTB4R2PPARGBRS3 | |
| SCHEMBL7906993 | 0.69 | FNTA (0.40) | FNTAFNTBLTB4R2PPARGBRS3 | |
| SCHEMBL7908230 | 0.69 | LTB4R2 (0.40) | FNTAFNTBLTB4R2 | |
| SCHEMBL7871095 | 0.67 | LTB4R2 (0.38) | LTB4R2PPARGPPARAFAAH | |
| SCHEMBL7918553 | 0.67 | SLC6A4 (0.41) | FNTAFNTB | |
| SCHEMBL7918101 | 0.64 | MYC (0.46) | FNTAFNTBPPARGPPARAMCL1 | |
| SCHEMBL7904963 | 0.63 | SLC6A4 (0.37) | FNTAFNTBLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |