Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21255686 | 0.91 | DRD2 (0.39) | DRD2DRD3ACHEALDH1A1DRD4 | |
| SCHEMBL22005149 | 0.73 | DRD2 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL7355600 | 0.68 | DRD3 (0.44) | DRD2DRD3ACHEDRD4 | |
| SCHEMBL7355604 | 0.68 | DRD3 (0.44) | DRD2DRD3ACHEDRD4 | |
| SCHEMBL7342652 | 0.67 | DRD2 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL7336693 | 0.67 | DRD2 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL7336689 | 0.67 | DRD2 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL7342658 | 0.67 | DRD2 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL8073107 | 0.66 | DRD1 (0.41) | DRD2DRD3ACHEDRD4 | |
| SCHEMBL7333795 | 0.66 | DRD3 (0.46) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097091-A1 | METHODS OF ADMINISTERING (4AR, 1OAR)-I-N-PROPYL-I, 2,3,4A7 S1IO7 IOA-OCTAHYDROBENZO [G] QUINOLINE-6,7-DIOL AND RELATED COMPOUNDS ACROSS THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN AND PHARMACEUTICAL COMPOSITIONS THEREOF | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |