Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MDH2 | P40926 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908069 | 0.94 | FFAR1 (0.55) | MAOBFFAR1LTB4RLTB4R2NR4A2 | |
| SCHEMBL7908047 | 0.93 | MAOB (0.55) | MAOBFFAR1LTB4RLTB4R2NR4A2 | |
| SCHEMBL21924233 | 0.93 | MAOB (0.60) | MAOBLTB4RLTB4R2NR4A2NR4A1 | |
| SCHEMBL4756552 | 0.90 | MAOB (0.63) | MAOBLTB4RLTB4R2NR4A2NR4A1 | |
| SCHEMBL21924280 | 0.89 | ALDH1A1 (0.60) | MAOBLTB4RLTB4R2NR4A2NR4A1 | |
| SCHEMBL7901154 | 0.87 | FFAR1 (0.54) | MAOBFFAR1LTB4RLTB4R2NR4A2 | |
| SCHEMBL7909000 | 0.87 | MAOB (0.58) | MAOBLTB4RLTB4R2NR4A2NR4A1 | |
| SCHEMBL7901066 | 0.87 | MAOB (0.54) | MAOBFFAR1LTB4RLTB4R2FFAR4 | |
| SCHEMBL6042635 | 0.85 | MEN1 (0.57) | MAOBLTB4RLTB4R2NR4A2NR4A1 | |
| SCHEMBL7908630 | 0.84 | NR4A2 (0.60) | MAOBNR4A2MCL1SLC16A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |