Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908527 | 1.00 | CETP (0.47) | CETPABCB1NR1H2NR1H3KLK7 | |
| SCHEMBL13609033 | 0.87 | CETP (0.46) | CETPABCB1NR1H2NR1H3KLK7 | |
| SCHEMBL7918130 | 0.87 | CETP (0.48) | CETPABCB1NR1H2NR1H3KLK7 | |
| SCHEMBL7918131 | 0.87 | CETP (0.48) | CETPABCB1NR1H2NR1H3KLK7 | |
| SCHEMBL14311138 | 0.87 | CETP (0.46) | CETPABCB1NR1H2NR1H3KLK7 | |
| SCHEMBL30360907 | 0.86 | ALDH1A1 (0.46) | CETPSTSGPR119 | |
| SCHEMBL29273726 | 0.86 | ALDH1A1 (0.46) | CETPSTSGPR119 | |
| SCHEMBL29273729 | 0.86 | ALDH1A1 (0.46) | CETPSTSGPR119 | |
| SCHEMBL14592677 | 0.85 | ABCB1 (0.45) | CETPABCB1KLK7STSGPR119 | |
| SCHEMBL2432631 | 0.85 | ABCB1 (0.45) | CETPABCB1KLK7STSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |