Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811050 | 0.89 | RORC (0.56) | RORCMEN1KMT2AALDH1A1HTT | |
| SCHEMBL6815381 | 0.88 | RORC (0.58) | RORCMEN1KMT2AALDH1A1ESRRA | |
| SCHEMBL6814919 | 0.88 | RORC (0.54) | RORCMEN1KMT2AALDH1A1ESRRA | |
| SCHEMBL6816236 | 0.87 | RORC (0.73) | RORCMEN1KMT2AALDH1A1ESRRA | |
| SCHEMBL6816131 | 0.87 | RORC (0.53) | RORCMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7638372 | 0.86 | RORC (0.55) | RORCMEN1KMT2AALDH1A1HTT | |
| SCHEMBL6815907 | 0.83 | ALDH1A1 (0.54) | RORCMEN1KMT2AALDH1A1HTT | |
| SCHEMBL6810840 | 0.83 | RORC (0.54) | RORCMEN1KMT2AALDH1A1ESRRA | |
| SCHEMBL6816205 | 0.82 | RORC (0.53) | RORCMEN1KMT2AALDH1A1ESRRA | |
| SCHEMBL7908567 | 0.82 | RORC (0.61) | RORCMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |