Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.56 |
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811686 | 0.90 | SMN1; SMN2 (0.60) | PPARDPPARGFFAR1ELANE | |
| SCHEMBL7908824 | 0.88 | PARP10 (0.54) | NR4A2NR4A1NR4A3MAOB | |
| SCHEMBL4364373 | 0.87 | NR4A2 (0.55) | PTPN1NR4A2NR4A1NR4A3MAOB | |
| SCHEMBL13412635 | 0.87 | ALOX5 (0.63) | MAOB | |
| SCHEMBL9797681 | 0.87 | SMN1; SMN2 (0.60) | PPARDPPARGELANE | |
| SCHEMBL29184830 | 0.84 | MAOB (0.70) | PPARDPPARGFFAR1MAOB | |
| SCHEMBL7914606 | 0.84 | NPC1 (0.56) | PPARDPPARGFFAR1MAOB | |
| SCHEMBL5883010 | 0.83 | PTGDR2 (0.60) | PPARDPPARGFFAR1MAOB | |
| SCHEMBL3920660 | 0.82 | PTPN7 (0.53) | PPARDPPARGFFAR1ELANEF2 | |
| SCHEMBL1115002 | 0.82 | PPARG (0.71) | PPARDPPARGFFAR1NR4A2PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |