Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | CTSG | P08311 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797681 | 0.94 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBPPARDPPARGNPC1 | |
| SCHEMBL7909009 | 0.90 | PPARD (0.59) | PPARDPPARGFFAR1ELANE | |
| SCHEMBL18623122 | 0.87 | MAOB (0.62) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL25685569 | 0.84 | POLB (0.64) | SMN1; SMN2POLBPPARDFFAR1ELANE | |
| SCHEMBL19712578 | 0.83 | MAOB (0.55) | SMN1; SMN2POLBNPC1HPGDRAB9A | |
| SCHEMBL29184830 | 0.83 | MAOB (0.70) | SMN1; SMN2PPARDPPARGFFAR1 | |
| SCHEMBL3176485 | 0.82 | LMNA (0.62) | SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9749418 | 0.81 | MAOB (0.59) | SMN1; SMN2PPARDPPARGFFAR1NPC1 | |
| SCHEMBL25196656 | 0.81 | MAOB (0.69) | POLBNPC1HPGDRAB9AMEN1 | |
| SCHEMBL9811660 | 0.81 | HPGD (0.57) | SMN1; SMN2POLBNPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064861-A | ACYLATED AMINE COMPOUNDS WHICH ARE USEFUL FUNGICIGAL AGENTS | ROUSSEL UCLAF (FR) | 1991-11-12 | — | — | US | disclosed |