Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907663 | 0.88 | NPC1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8494317 | 0.83 | MAOB (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1921737 | 0.82 | EGLN1 (0.52) | MEN1KMT2ASPHK2L3MBTL1 | |
| SCHEMBL29564198 | 0.82 | EGLN1 (0.52) | MEN1KMT2ASPHK2L3MBTL1 | |
| SCHEMBL834204 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3962253 | 0.81 | MAOB (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14009671 | 0.79 | KDM4E (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL384341 | 0.78 | MAOB (0.78) | SMN1; SMN2MAOBMAPTL3MBTL1 | |
| SCHEMBL29369517 | 0.78 | MAOB (0.78) | SMN1; SMN2MAOBMAPTL3MBTL1 | |
| SCHEMBL5446276 | 0.78 | L3MBTL1 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |