Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | RXRA | P19793 | 3/20 | 0.58 |
| ▸ | RXRB | P28702 | 3/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973613 | 0.94 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2SRD5A2RXRARXRB | |
| SCHEMBL3741672 | 0.94 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2SRD5A2RXRARXRB | |
| SCHEMBL15569594 | 0.90 | BCL2L1 (0.58) | SRD5A2RXRARXRBBCL2L1BAD | |
| SCHEMBL13888048 | 0.88 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2SRD5A2RXRARXRB | |
| SCHEMBL308875 | 0.88 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2SRD5A2RXRARXRB | |
| SCHEMBL15725684 | 0.85 | MAPT (0.53) | ALDH1A1SMN1; SMN2ALOX5KDM4EGAA | |
| SCHEMBL18390948 | 0.85 | MAPT (0.53) | ALDH1A1SMN1; SMN2ALOX5KDM4EGAA | |
| SCHEMBL21760526 | 0.84 | EGFR (0.53) | ALDH1A1SRD5A2RXRARXRBPTGES | |
| SCHEMBL14769783 | 0.84 | EGFR (0.53) | ALDH1A1SRD5A2RXRARXRBPTGES | |
| SCHEMBL17040204 | 0.83 | TSHR (0.67) | ALDH1A1SMN1; SMN2SRD5A2BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284365-B1 | FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE | FUJI XEROX CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |