SCHEMBL8973613

SCHEMBL8973613

Cc1ccc(N(c2ccc(C(=O)O)cc2)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
SRD5A2 P31213 3/20 0.65
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
LMNA P02545 2/20 0.50
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
NPC1 O15118 2/20 0.48
POLB P06746 1/20 0.48
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
AKR1C3 P42330 1/20 0.46
PKM P14618 2/20 0.45
HTT P42858 2/20 0.45
ATM Q13315 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3741672 1.00 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
SCHEMBL7909102 0.94 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
SCHEMBL2029621 0.89 TSHR (0.67) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
SCHEMBL17040204 0.89 TSHR (0.67) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
SCHEMBL22972761 0.89 TSHR (0.67) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Terephthalic Acid SCHEMBL526449 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL1331178 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Terephthalic Acid SCHEMBL15994097 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL11366477 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL93638 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5536866-A Triarylamine-based dinitrile and dicarboxylic acid monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1996-07-16 US disclosed
US-5534613-A ELECTROCONDUCTORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1996-07-09 US disclosed