SCHEMBL7909294

SCHEMBL7909294

NC1=NC2(CCc3c(/C=N/O)cccc3C2)CO1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.55
ADRA2A P08913 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921326 0.85 ADRA2A (0.52) TAAR1ADRA2A
SCHEMBL15080215 0.79 TAAR1 (0.61) TAAR1ADRA2A
SCHEMBL7923317 0.79 TAAR1 (0.61) TAAR1ADRA2A
SCHEMBL7924157 0.78 TAAR1 (0.57) TAAR1ADRA2A
SCHEMBL7916938 0.77 ADRA2A (0.59) TAAR1ADRA2A
SCHEMBL7923463 0.76 TAAR1 (0.55) TAAR1ADRA2A
SCHEMBL7918292 0.74 ADRA2A (0.52) TAAR1ADRA2A
SCHEMBL7925689 0.74 ADRA2A (0.52) TAAR1ADRA2A
SCHEMBL7917980 0.73 TAAR1 (0.54) TAAR1ADRA2A
SCHEMBL7924445 0.73 TAAR1 (0.54) TAAR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010042475-A1 SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS SCHERING CORPORATION (US) 2010-04-15 WO disclosed