⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721712 | 0.94 | KMT2A (0.33) | — | |
| SCHEMBL29407115 | 0.89 | ALDH1A1 (0.37) | — | |
| SCHEMBL29353135 | 0.86 | THRB (0.34) | — | |
| SCHEMBL29430956 | 0.86 | ALDH1A1 (0.34) | — | |
| SCHEMBL7912887 | 0.85 | — | — | |
| SCHEMBL28333248 | 0.83 | THRB (0.41) | — | |
| SCHEMBL19513944 | 0.82 | THRB (0.37) | — | |
| SCHEMBL11253245 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL11253248 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL9699425 | 0.80 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197289-B1 | Removal of biologically active agents | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6146771-A | Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| EP-1021216-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | Terumo Cardiovascular Systems Corporation (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-0994745-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | Terumo Cardiovascular Systems Corporation (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001167-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001195-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |