Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904520 | 0.87 | KMT2A (0.46) | KMT2ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL517417 | 0.86 | TP53 (0.42) | KMT2ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7903336 | 0.85 | KMT2A (0.45) | KMT2ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7602899 | 0.81 | LMNA (0.50) | KMT2ATP53PGRHRH3POLB | |
| SCHEMBL517569 | 0.80 | TP53 (0.40) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL7605776 | 0.80 | KMT2A (0.47) | KMT2ATP53PGRHRH3POLB | |
| SCHEMBL13660764 | 0.80 | TP53 (0.48) | KMT2ATP53PGRHRH3POLB | |
| SCHEMBL7604168 | 0.79 | KMT2A (0.48) | KMT2ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7899898 | 0.79 | KMT2A (0.45) | KMT2ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL517336 | 0.79 | TP53 (0.41) | TP53CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102717-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-16 | — | — | WO | disclosed |