Diphenylsulfane

Diphenylsulfane

SCHEMBL7909499

O=S(=O)(OC(F)(F)F)C(F)(F)F.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
MMP13 P45452 3/20 0.37
MMP8 P22894 2/20 0.37
MMP3 P08254 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
BCL2 P10415 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915292 0.92 CA12 (0.37) PTGS1PTGS2CA1CA2CA12
SCHEMBL2569852 0.79 STS (0.53) PTGS1PTGS2CA1CA2CA12
Diphenylsulfane SCHEMBL673319 0.79 STS (0.53) PTGS1PTGS2CA1CA2CA12
Diphenylsulfane SCHEMBL6382661 0.78 ALDH1A1 (0.44) PTGS1PTGS2CA1CA2CA12
Diphenylsulfane SCHEMBL31170665 0.76 ALDH1A1 (0.42) PTGS1PTGS2CA1CA2CA12
SCHEMBL286824 0.76 CA1 (0.37) CA1CA2CA7CA13
Diphenylsulfane SCHEMBL672234 0.75 CA1 (0.51) CA1CA2CA12HPGDMAOA
Biphenyl SCHEMBL21461722 0.75 STS (0.49) PTGS1PTGS2CA1CA2CA12
Diphenylsulfane SCHEMBL674158 0.75 STS (0.44) PTGS1PTGS2CA1CA2CA12
Diphenylsulfane SCHEMBL672139 0.74 PPARG (0.45) PTGS1PTGS2CA1CA2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6215021-B1 TRIFLUOROMETHYL DIPHENYLSULFONIUM TRIFLATE DERIVATIVES IDAHO RESEARCH FOUNDATION, INC. 2001-04-10 US claimed
US-6215021-B1 TRIFLUOROMETHYL DIPHENYLSULFONIUM TRIFLATE DERIVATIVES IDAHO RESEARCH FOUNDATION, INC. 2001-04-10 US disclosed
US-6215021-B1 TRIFLUOROMETHYL DIPHENYLSULFONIUM TRIFLATE DERIVATIVES IDAHO RESEARCH FOUNDATION, INC. 2001-04-10 US disclosed