Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.70 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722732 | 0.81 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL6948894 | 0.81 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5722927 | 0.77 | PDE4D (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5722709 | 0.76 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5723223 | 0.76 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7054247 | 0.76 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL5723221 | 0.75 | PDE4D (0.46) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL13210698 | 0.75 | KCNMA1 (0.74) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL14322300 | 0.74 | S1PR1 (0.68) | PDE4APDE4BPDE4CPDE4DKCNMA1 | |
| SCHEMBL5023240 | 0.74 | PDE4B (0.63) | PDE4APDE4BPDE4CPDE4DKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211203-B1 | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-04-03 | — | — | US | disclosed |