Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904909 | 0.88 | RAB9A (0.67) | RAB9AITGB3ITGA2BCYP3A4 | |
| SCHEMBL17999901 | 0.85 | ITGB3 (0.53) | RAB9AITGB3ITGA2BF2PLG | |
| Hydrochloric Acid SCHEMBL17969235 | 0.84 | ITGB3 (0.55) | RAB9AITGB3ITGA2BF2PLG | |
| SCHEMBL17999904 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL7903531 | 0.84 | F2 (0.56) | RAB9AITGB3ITGA2BF2PLG | |
| SCHEMBL16634809 | 0.83 | ITGB3 (0.49) | RAB9AITGB3ITGA2BF2PLG | |
| Hydrochloric Acid SCHEMBL17969256 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BF2PLGPLAU | |
| Hydrochloric Acid SCHEMBL17969248 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BF2PLGPLAU | |
| Hydrochloric Acid SCHEMBL31174279 | 0.82 | F2 (0.55) | RAB9AITGB3ITGA2BF2PLG | |
| SCHEMBL3658561 | 0.82 | F2 (0.57) | ITGB3ITGA2BF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |