Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552606 | 0.90 | MEN1 (0.52) | MEN1KMT2ATSHRRAB9AMAPT | |
| SCHEMBL11755275 | 0.81 | POLB (0.54) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10527436 | 0.81 | ATM (0.43) | MEN1KMT2ATSHRMAPTNPC1 | |
| SCHEMBL9396448 | 0.80 | POLB (0.55) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10413873 | 0.80 | KMT2A (0.71) | MEN1KMT2ATSHRRAB9APOLB | |
| SCHEMBL8933428 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ATSHRRAB9AMAPT | |
| SCHEMBL8933437 | 0.78 | TP53 (0.42) | MEN1KMT2ATSHRRAB9AMAPT | |
| SCHEMBL11225167 | 0.77 | MEN1 (0.56) | MEN1KMT2ATSHRPOLBKDM4E | |
| SCHEMBL8697187 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2ATSHRRAB9AMAPT | |
| SCHEMBL7950734 | 0.75 | RAB9A (0.55) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |