SCHEMBL7909983

SCHEMBL7909983

C=C(C)C(=O)OCCC[Si](OC)(OC)OC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
THRB P10828 1/20 0.42
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635661 0.97 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL143449 0.92 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7637126 0.90 THRB (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28347798 0.90 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.90 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5446210 0.90 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28744295 0.90 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20787785 0.89 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23437 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
Hydrogen Sulfide SCHEMBL329768 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1293216-A Polyolefinic resin for coating silicon dioxide and its preparation method NIPPON SHEET GLASS CO LTD (JP) 2001-05-02 CN disclosed
EP-1094090-A2 Silicon dioxide-coated polyolefin resin and process for its production NIPPON SHEET GLASS CO. LTD. (JP) 2001-04-25 EP disclosed