SCHEMBL7910000

SCHEMBL7910000

COC(=O)c1ccc(COCc2ccc(-c3ccccc3)o2)cc1-c1ccccc1C

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 19/20 0.64
FNTB P49356 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905477 0.81 FNTA (0.49) FNTAFNTB
SCHEMBL8589974 0.81 FNTA (0.87) FNTAFNTB
SCHEMBL8589977 0.81 FNTA (0.87) FNTAFNTB
SCHEMBL7907281 0.80 FNTA (0.85) FNTAFNTB
Lithium SCHEMBL7907284 0.80 FNTA (0.85) FNTAFNTB
Dimethylamine SCHEMBL8590057 0.80 FNTA (0.84) FNTAFNTB
SCHEMBL7905941 0.80 FNTA (0.44) FNTAFNTB
Dimethylamine SCHEMBL7904862 0.79 FNTA (0.83) FNTAFNTB
Lithium Ion SCHEMBL7907277 0.79 FNTA (1.00) FNTAFNTB
SCHEMBL8590277 0.78 FNTA (0.86) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed