Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.49 |
| ▸ | FNTB | P49356 | 19/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905941 | 0.83 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL7903834 | 0.83 | FNTA (0.43) | FNTAFNTBKDM4E | |
| SCHEMBL7910000 | 0.81 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7910598 | 0.81 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7910206 | 0.80 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7903687 | 0.80 | FNTA (0.78) | FNTAFNTB | |
| SCHEMBL7903684 | 0.80 | FNTA (0.78) | FNTAFNTB | |
| SCHEMBL7906928 | 0.79 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7906924 | 0.79 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7903816 | 0.78 | FNTA (0.42) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |