Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.30 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910310 | 0.78 | SCN8A (0.34) | MAPTKDM4ELMNASMN1; SMN2SCN8A | |
| SCHEMBL7922620 | 0.78 | MEN1 (0.53) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL7919718 | 0.77 | POLB (0.32) | ALDH1A1MAPTKDM4ENSD2LMNA | |
| SCHEMBL7917015 | 0.74 | DRD4 (0.32) | LMNAALKBH5DRD4MEN1NR1I2 | |
| SCHEMBL5566905 | 0.69 | MEN1 (0.65) | MEN1NR1I2KMT2A | |
| SCHEMBL7919224 | 0.65 | MEN1 (0.33) | ALDH1A1MAPTKDM4ENSD2LMNA | |
| SCHEMBL9823338 | 0.65 | MDM2 (0.33) | MAPTALKBH5MEN1NR1I2KMT2A | |
| SCHEMBL5566928 | 0.65 | MEN1 (0.59) | MEN1NR1I2KMT2A | |
| SCHEMBL7922537 | 0.65 | MAPT (0.39) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL1979065 | 0.65 | TSHR (0.44) | LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |