SCHEMBL1979065

SCHEMBL1979065

OCC(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
MAPK1 P28482 2/20 0.44
HIF1A Q16665 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALOX15 P16050 1/20 0.44
LMNA P02545 4/20 0.44
GABBR2 O75899 3/20 0.44
GABBR1 Q9UBS5 3/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
NFKB1 P19838 1/20 0.44
DRD3 P35462 1/20 0.44
BLM P54132 1/20 0.44
CYP1A2 P05177 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058257 0.93 IDO1 (0.50) TSHRLMNACYP2C9CYP2D6CYP2C19
SCHEMBL14830681 0.85 ACP3 (0.46) TSHRLMNAMEN1KMT2AADRB2
SCHEMBL19984896 0.84 TDP1 (0.51) TSHRMAPK1TDP1CYP2C9MEN1
SCHEMBL15617661 0.84 MAOA (0.48) TSHRLMNACYP2C9CYP2D6CNR1
SCHEMBL27394453 0.82 AOC3 (0.42) TSHRLMNAGABBR2GABBR1CYP2C9
SCHEMBL15617660 0.81 CYP2C19 (0.51) TSHRTDP1LMNACYP2C9CYP2C19
SCHEMBL1155162 0.79 GABBR2 (0.48) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL2697966 0.79 TSHR (0.44) TSHRMAPK1HIF1ATDP1ALOX15
SCHEMBL1155443 0.77 AOC3 (0.53) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL5437078 0.77 AOC3 (0.53) TSHRMAPK1HIF1ATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051971-A Safety control method and system for new energy power system 南通职业大学 2026-05-15 CN claimed
CN-118629078-B Multi-modal face recognition and prototype reconstruction method based on VAE-GAN framework 南昌大学 2025-01-21 CN claimed
CN-118629078-A Multi-modal face recognition and prototype reconstruction method based on VAE-GAN framework 南昌大学 2024-09-10 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
CN-122051971-A Safety control method and system for new energy power system 南通职业大学 2026-05-15 CN disclosed
US-20260091064-A1 METHOD FOR ISOLATION AND PURIFICATION OF MICROVESICLES FROM CELL CULTURE SUPERNATANTS AND BIOLOGICAL FLUIDS UNIV MIAMI (US) 2026-04-02 US disclosed
US-12558316-B2 Methods and compositions for the treatment of epidermolysis bullosa UNIVERSITY OF MIAMI (US) 2026-02-24 US disclosed
US-12497527-B2 Ink, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2025-12-16 US disclosed
US-12453745-B2 Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids UNIVERSITY OF MIAMI (US) 2025-10-28 US disclosed
EP-3686254-B1 INK, METHOD OF MANUFACTURING INK, PRINTING METHOD, AND PRINTING DEVICE RICOH CO LTD (JP) 2025-03-12 EP disclosed
EP-4511045-A1 COMPOSITIONS COMPRISING MICROVESICLES FOR USE IN THE PREVENTION AND TREATMENT OF GRAFT VERSUS HOST DISEASE University of Miami (US) 2025-02-26 EP disclosed
US-5468748-A Nervous system and psychological disorders; antagonize glycine binding site on N-methylaspartic acid receptor complex NOVO NORDISK A/S (DK) 1995-11-21 US disclosed
WO-1994018175-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-08-18 WO disclosed
EP-0124287-B1 METHOD AND TEST COMPOSITION FOR DETERMINATION OF HYDROGEN PEROXIDE Kyowa Medex Co. Ltd. (JP) 1993-03-03 EP disclosed
EP-0013307-B1 LIQUID FOLIAR FERTILIZER COMPOSITIONS CONTAINING WATER-SOLUBLE UREA-FORMALDEHYDE PRODUCTS ALLIED CORPORATION (US) 1984-09-05 EP disclosed
EP-0013307-A1 Liquid foliar fertilizer compositions containing water-soluble urea-formaldehyde products ALLIED CORPORATION (US) 1980-07-23 EP disclosed
US-4105762-A Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4035173-A CONIFERS, PINACEAE UREA, AMMONIA, AMMONIUM SULFATES, NITRATES OF AMMONIA, CALCIUM AND POTASSIUM UNION OIL COMPANY OF CALIFORNIA (US) 1977-07-12 US disclosed
US-4033747-A CONIFERS UNION OIL COMPANY OF CALIFORNIA (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558316-B2 Methods and compositions for the treatment of epidermolysis bullosa COL14A1, EPCAM, KRT18 TSHR 857/4885MAPK1 1800/4885HIF1A 1170/4885
US-20260091064-A1 METHOD FOR ISOLATION AND PURIFICATION OF MICROVESICLES FROM CELL CULTURE SUPERNATANTS AND BIOLOGICAL FLUIDS CXCL12, ICOS, CCL5 TSHR 2494/4885MAPK1 1754/4885HIF1A 3345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.