Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975752 | 0.89 | SMN1; SMN2 (0.54) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL27294490 | 0.82 | NPSR1 (0.44) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL13965862 | 0.82 | NPSR1 (0.44) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL8446138 | 0.82 | TSHR (0.44) | SMN1; SMN2POLBL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8444370 | 0.80 | TSHR (0.43) | SMN1; SMN2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6891739 | 0.79 | KCNN4 (0.48) | L3MBTL1KMT2ALMNATDP1CYP2C19 | |
| SCHEMBL20788472 | 0.73 | MIF (0.52) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL10232620 | 0.73 | CYP1A2 (0.41) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL5301475 | 0.72 | MEN1 (0.52) | NPSR1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL7875274 | 0.69 | NPSR1 (0.40) | NPSR1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |