Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8444370 | 0.98 | TSHR (0.43) | TSHRNPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL22430335 | 0.83 | TSHR (0.48) | TSHRNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8350785 | 0.82 | TSHR (0.43) | TSHRNPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL7910319 | 0.82 | NPSR1 (0.46) | TSHRNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6891739 | 0.81 | KCNN4 (0.48) | L3MBTL1TDP1HTR1ACYP2D6SCN1A | |
| SCHEMBL8029072 | 0.73 | TSHR (0.52) | TSHRNPC1RAB9AMAPTTDP1 | |
| SCHEMBL9906142 | 0.72 | TSHR (0.57) | TSHRNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29657118 | 0.71 | HPGD (0.42) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10538653 | 0.71 | ESR1 (0.52) | TSHRL3MBTL1SMN1; SMN2HPGDACHE | |
| SCHEMBL13786376 | 0.71 | ATM (0.59) | TSHRRAB9AMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |