Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910319 | 0.89 | NPSR1 (0.46) | SMN1; SMN2POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL10538653 | 0.81 | ESR1 (0.52) | SMN1; SMN2POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL11922815 | 0.81 | KCNN4 (0.45) | POLBL3MBTL1HDAC3HDAC1HDAC2 | |
| Bromide SCHEMBL28991574 | 0.79 | KCNN4 (0.44) | POLBL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL13965862 | 0.79 | NPSR1 (0.44) | SMN1; SMN2POLBL3MBTL1NPSR1LMNA | |
| SCHEMBL27294490 | 0.79 | NPSR1 (0.44) | SMN1; SMN2POLBL3MBTL1NPSR1LMNA | |
| SCHEMBL10232620 | 0.77 | CYP1A2 (0.41) | SMN1; SMN2POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL29361985 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL27553464 | 0.75 | CNR2 (0.43) | SMN1; SMN2L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL28254515 | 0.75 | ABL1 (0.43) | SMN1; SMN2POLBL3MBTL1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLOUNT KENNETH F (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | SMN1; SMN2 4259/4885POLB 1461/4885L3MBTL1 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.