Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.50 |
| ▸ | KDR | P35968 | 7/20 | 0.50 |
| ▸ | FLT3 | P36888 | 7/20 | 0.50 |
| ▸ | LCK | P06239 | 4/20 | 0.50 |
| ▸ | CSF1R | P07333 | 4/20 | 0.50 |
| ▸ | LYN | P07948 | 4/20 | 0.50 |
| ▸ | FLT1 | P17948 | 4/20 | 0.50 |
| ▸ | FLT4 | P35916 | 4/20 | 0.50 |
| ▸ | BLK | P51451 | 4/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889198 | 0.77 | ALDH1A1 (0.47) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL18368425 | 0.73 | CYP1A2 (0.43) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL12016953 | 0.73 | MAPK1 (0.47) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL29957225 | 0.73 | MAPK1 (0.47) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL2768727 | 0.71 | MAPK8 (0.52) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL14469774 | 0.71 | TTK (0.40) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL8336855 | 0.71 | CDK2 (0.65) | KITKDRFLT3LCKCSF1R | |
| SCHEMBL19609001 | 0.69 | ALDH1A1 (0.61) | ALDH1A1TSHRCYP1A2KDM4EMEN1 | |
| SCHEMBL1765158 | 0.69 | TSHR (0.67) | ALDH1A1TSHRCYP1A2KDM4EMEN1 | |
| SCHEMBL29955303 | 0.68 | CYP2A6 (0.39) | KITKDRFLT3LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102070-A1 | METHODS OF TREATING HPV-ASSOCIATED CANCER WITH JNK INHIBITORS | ARBOR VITA CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |