Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20132828 | 0.80 | LMNA (0.45) | LMNAL3MBTL1TDP1CYP2C19ALDH1A1 | |
| SCHEMBL20132790 | 0.80 | LMNA (0.45) | LMNAL3MBTL1TDP1CYP2C19ALDH1A1 | |
| SCHEMBL7910919 | 0.80 | MEN1 (0.43) | LMNAL3MBTL1TDP1TEAD3ALDH1A1 | |
| SCHEMBL900165 | 0.79 | TDP1 (0.57) | LMNAL3MBTL1TDP1ALDH1A1MMP8 | |
| SCHEMBL23620881 | 0.78 | L3MBTL1 (0.51) | LMNAL3MBTL1TDP1CYP2C19ALDH1A1 | |
| SCHEMBL20180360 | 0.78 | L3MBTL1 (0.51) | LMNAL3MBTL1TDP1CYP2C19ALDH1A1 | |
| SCHEMBL20180712 | 0.78 | L3MBTL1 (0.51) | LMNAL3MBTL1TDP1CYP2C19ALDH1A1 | |
| SCHEMBL20057281 | 0.78 | L3MBTL1 (0.43) | LMNAL3MBTL1TDP1TEAD3ALDH1A1 | |
| SCHEMBL12677778 | 0.77 | TDP1 (0.55) | LMNAL3MBTL1TDP1ALDH1A1MMP8 | |
| SCHEMBL18355825 | 0.76 | TDP1 (0.50) | LMNAL3MBTL1TDP1ALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211360-B1 | DRUG ABRUSE THERAPY; PLANT EXTRACTS | ALBANY MEDICAL COLLEGE | 2001-04-03 | — | — | US | disclosed |