Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911356 | 0.88 | ALDH1A1 (0.50) | MCL1ALDH1A1SCN9A | |
| SCHEMBL15716510 | 0.81 | ALDH1A1 (0.58) | MCL1CTSVCTSLALDH1A1PTGER1 | |
| SCHEMBL16719453 | 0.80 | NPC1 (0.48) | MCL1CTSVCTSLALDH1A1PTGER1 | |
| SCHEMBL28547789 | 0.77 | ALDH1A1 (0.52) | CTSVCTSLALDH1A1PTGER1NR4A2 | |
| SCHEMBL402519 | 0.76 | ALDH1A1 (0.50) | MCL1ALDH1A1DHODHNR4A2NR4A1 | |
| SCHEMBL3424839 | 0.76 | ALDH1A1 (0.55) | MCL1ALDH1A1PTGER1NR4A2FOLH1 | |
| SCHEMBL8797209 | 0.76 | PTGER1 (0.55) | MCL1CTSVCTSLALDH1A1PTGER1 | |
| SCHEMBL8673772 | 0.75 | TDP1 (0.54) | MCL1CTSVCTSLALDH1A1PTGER1 | |
| SCHEMBL1305739 | 0.75 | PTGER1 (0.61) | MCL1CTSVCTSLALDH1A1PTGER1 | |
| Hydrochloric Acid SCHEMBL2707920 | 0.74 | ALDH1A1 (0.48) | MCL1ALDH1A1DHODHNR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |