Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 16/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913006 | 0.82 | ALDH1A1 (0.56) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9266309 | 0.79 | NOTUM (0.65) | NOTUMKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9551842 | 0.75 | NOTUM (0.40) | NOTUMMAPK1 | |
| SCHEMBL9260755 | 0.74 | CLCN2 (0.57) | NOTUMMEN1GMNNLMNACYP3A4 | |
| SCHEMBL31141591 | 0.74 | NOTUM (0.59) | NOTUM | |
| SCHEMBL18394900 | 0.72 | NOTUM (1.00) | NOTUM | |
| SCHEMBL9823666 | 0.72 | NOTUM (0.65) | NOTUMKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL3943150 | 0.72 | NOTUM (0.65) | NOTUMKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13723672 | 0.72 | NOTUM (1.00) | NOTUMKDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5542637 | 0.71 | NOTUM (1.00) | NOTUMKDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | claimed |
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | disclosed |