Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911134 | 1.00 | GPR84 (0.36) | GPR84MAOBMAOAALDH1A1LMNA | |
| SCHEMBL16762080 | 0.88 | GPR84 (0.42) | GPR84MAOBMAOAALDH1A1LMNA | |
| SCHEMBL8727564 | 0.81 | ESR2 (0.41) | MAOBMAOAALDH1A1LMNAMAPT | |
| SCHEMBL8727559 | 0.81 | ESR2 (0.41) | MAOBMAOAALDH1A1LMNAMAPT | |
| SCHEMBL9949415 | 0.81 | GPR84 (0.38) | GPR84MAOBMAOAALDH1A1LMNA | |
| SCHEMBL9949678 | 0.81 | MAOB (0.42) | GPR84MAOBMAOAALDH1A1LMNA | |
| SCHEMBL9950189 | 0.81 | MAOB (0.39) | GPR84MAOBMAOAALDH1A1LMNA | |
| SCHEMBL9950282 | 0.80 | DAO (0.42) | GPR84ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7553134 | 0.78 | ESR2 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL7553137 | 0.78 | ESR2 (0.39) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132377-A1 | Propiolonitrile derivatives and liquid crystal compositions comprising the same | CHISSO CORPORATION (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6017467-A | HEAT AND CHEMICAL RESISTANCE | CHISSO CORPORATION (JP) | 2000-01-25 | — | — | US | disclosed |
| CN-1174832-A | Propiolonitrile derivatives and liquid crystal compositions comprising the same | CHISSO CORP (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0816332-A1 | Propiolonitrile derivatives and liquid crystal compositions comprising the same | Chisso Corporation (JP) | 1998-01-07 | — | — | EP | disclosed |