SCHEMBL7911166

SCHEMBL7911166

CCC1CCC(c2ccc(/C=C/c3ccc(OC(F)(F)C(F)C(F)(F)F)c(Cl)c3)cc2)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.32
RECQL P46063 1/20 0.32
CCR2 P41597 7/20 0.32
PDE4B Q07343 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911169 1.00 FBP1 (0.32) FBP1RECQLCCR2PDE4BEPHX2
SCHEMBL7911807 0.90 MEN1 (0.30)
SCHEMBL7911806 0.90 MEN1 (0.30)
SCHEMBL7917336 0.85 FBP1 (0.33) FBP1RECQLPDE4BEPHX2
SCHEMBL7917334 0.85 FBP1 (0.33) FBP1RECQLPDE4BEPHX2
SCHEMBL7917339 0.85 FBP1 (0.33) FBP1RECQLPDE4BEPHX2
SCHEMBL7913713 0.85 ALDH1A1 (0.39)
SCHEMBL7913714 0.85 ALDH1A1 (0.39)
SCHEMBL8834448 0.83 CYP2C9 (0.37) RECQLCCR2PDE4B
SCHEMBL8834444 0.83 CYP2C9 (0.37) RECQLCCR2PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed