Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 9/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916800 | 0.89 | CYP11B1 (0.32) | CYP11B1CYP11B2KIF11 | |
| SCHEMBL7914104 | 0.88 | ACACB (0.31) | ACACBACACAFFAR1 | |
| SCHEMBL7917509 | 0.88 | FFAR1 (0.30) | FFAR1 | |
| SCHEMBL7914052 | 0.87 | CYP2C9 (0.41) | CYP11B1CYP11B2KIF11DGAT1SOAT2 | |
| SCHEMBL7903736 | 0.85 | CYP11B1 (0.34) | CYP11B1CYP11B2KIF11 | |
| SCHEMBL7913858 | 0.84 | DGAT1 (0.34) | ACACBDGAT1SOAT1FFAR1 | |
| SCHEMBL7903474 | 0.84 | CYP2C9 (0.34) | KIF11DGAT1 | |
| SCHEMBL7903766 | 0.83 | RECQL (0.32) | ACACBACACADGAT1FFAR1 | |
| SCHEMBL8834962 | 0.83 | FFAR4 (0.33) | ACACBACACA | |
| SCHEMBL7911079 | 0.81 | ESR2 (0.35) | CYP11B1CYP11B2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |