SCHEMBL7913858

SCHEMBL7913858

COCC1CCC(c2ccc(-c3ccc(C(F)(F)C(F)C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.34
SOAT1 P35610 1/20 0.34
HTR2C P28335 2/20 0.33
ACACB O00763 3/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ESR2 Q92731 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
CYP2C9 P11712 2/20 0.31
IDO1 P14902 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
APP P05067 1/20 0.31
FFAR1 O14842 1/20 0.30
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914093 0.93 HTR2C (0.33) HTR2CACACBALDH1A1LMNAMAPT
SCHEMBL7913629 0.88 ALDH1A1 (0.33) DGAT1SOAT1HTR2CACACBALDH1A1
SCHEMBL7914007 0.85 ALDH1A1 (0.39) DGAT1ACACBALDH1A1MAPTESR2
SCHEMBL7914104 0.85 ACACB (0.31) ACACBFFAR1
SCHEMBL8667366 0.84 HTR2C (0.47) DGAT1SOAT1HTR2CESR2IDO1
SCHEMBL7911750 0.84 MAOB (0.35)
SCHEMBL7911217 0.84 CYP11B1 (0.35) DGAT1SOAT1ACACBFFAR1
SCHEMBL7913753 0.83 HTR2C (0.31) DGAT1SOAT1HTR2CL3MBTL1IDO1
SCHEMBL7914043 0.81 MAPT (0.39) ALDH1A1LMNAMAPTCYP2C9
SCHEMBL7911931 0.81 ALDH1A1 (0.42) ACACBALDH1A1MAPTESR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed